Transcriptome Analysis Illuminates a Hub Role of SREBP2 in Cholesterol Metabolism by α-Mangostin

[Image: see text] Whole-transcriptome analysis of α-mangostin-treated HepG2 cells revealed that genes relevant to lipid and cholesterol metabolic processes responded to α-mangostin treatment. α-Mangostin downregulated a series of cholesterol biosynthetic genes, including SQLE, HMGCR, and LSS, and co...

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Vydáno v:ACS Omega
Hlavní autoři: Chae, Hee-Sung, Kim, Hyun Ji, Ko, Hyun-Jeong, Lee, Chang Hoon, Choi, Young Hee, Chin, Young-Won
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2020
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726933/
https://ncbi.nlm.nih.gov/pubmed/33324821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c04282
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