Inhibitory effects of α-Mangostin on T cell cytokine secretion via ORAI1 calcium channel and K(+) channels inhibition

BACKGROUND: As one of the main components of mangosteen (Garcinia mangostana), a tropical fruit, α-mangostin has been reported to have numerous pharmacological benefits such as anti-cancer, anti-inflammatory, and anti-allergic effects through various mechanisms of action. The effects of α-mangostin...

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Bibliographic Details
Published in:PeerJ
Main Authors: Kim, Hyun Jong, Park, Seorin, Shin, Hui Young, Nam, Yu Ran, Lam Hong, Phan Thi, Chin, Young-Won, Nam, Joo Hyun, Kim, Woo Kyung
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2021
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7936567/
https://ncbi.nlm.nih.gov/pubmed/33717700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10973
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