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Alternative splicing coupled mRNA decay shapes the temperature‐dependent transcriptome

Mammalian body temperature oscillates with the time of the day and is altered in diverse pathological conditions. We recently identified a body temperature‐sensitive thermometer‐like kinase, which alters SR protein phosphorylation and thereby globally controls alternative splicing (AS). AS can gener...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Neumann, Alexander, Meinke, Stefan, Goldammer, Gesine, Strauch, Miriam, Schubert, Daniel, Timmermann, Bernd, Heyd, Florian, Preußner, Marco
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726792/
https://ncbi.nlm.nih.gov/pubmed/33140569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051369
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