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N‐glycosylation of PD‐1 promotes binding of camrelizumab

PD‐1 is a highly glycosylated inhibitory receptor expressed mainly on T cells. Targeting of PD‐1 with monoclonal antibodies (MAbs) to block the interaction with its ligand PD‐L1 has been successful for the treatment of multiple tumors. However, polymorphisms at N‐glycosylation sites of PD‐1 exist in...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:EMBO Rep
Asıl Yazarlar: Liu, Kefang, Tan, Shuguang, Jin, Wanjun, Guan, Jiawei, Wang, Qingling, Sun, Huan, Qi, Jianxun, Yan, Jinghua, Chai, Yan, Wang, Zhongfu, Deng, Chuxia, Gao, George F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726772/
https://ncbi.nlm.nih.gov/pubmed/33063473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202051444
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