Carnosine alleviates diabetic nephropathy by targeting GNMT, a key enzyme mediating renal inflammation and fibrosis

Diabetic nephropathy (DN) is a common microvascular complication of diabetes and the main cause of end-stage nephropathy (ESRD). Inflammation and fibrosis play key roles in the development and progression of diabetic nephropathy. By using in vivo and in vitro DN models, our laboratory has identified...

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Detalhes bibliográficos
Publicado no:Clin Sci (Lond)
Main Authors: Liu, Xue-qi, Jiang, Ling, Lei, Lei, Nie, Zhen-yong, Zhu, Wei, Wang, Sheng, Zeng, Han-xu, Zhang, Shi-qi, Zhang, Qiu, Yard, Benito, Wu, Yong-gui
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2020
Assuntos:
Diabetes & Metabolic Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7726623/
https://ncbi.nlm.nih.gov/pubmed/33241846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20201207
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