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Structural Features of Heparin and Its Interactions With Cellular Prion Protein Measured by Surface Plasmon Resonance
Self-propagating form of the prion protein (PrP(Sc)) causes many neurodegenerative diseases, such as Creutzfeldt-Jakob disease (CJD) and Gerstmann-Straussler-Scheinker syndrome (GSS). Heparin is a highly sulfated linear glycosaminoglycan (GAG) and is composed of alternating D-glucosamine and L-iduro...
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| Publicado no: | Front Mol Biosci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7726446/ https://ncbi.nlm.nih.gov/pubmed/33324681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.594497 |
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