Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation

BACKGROUND & AIMS: Countries endemic for parasitic infestations have a lower incidence of Crohn’s disease (CD) than non-endemic countries, and there have been anecdotal reports of the beneficial effects of helminths in CD patients. Tuft cells in the small intestine sense and direct the immune re...

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Pubblicato in:Gastroenterology
Autori principali: Banerjee, Amrita, Herring, Charles A., Chen, Bob, Kim, Hyeyon, Simmons, Alan J., Southard-Smith, Austin N., Allaman, Margaret M., White, James R., Macedonia, Mary C., Mckinley, Eliot T., Solano, Marisol A. Ramirez, Scoville, Elizabeth A., Liu, Qi, Wilson, Keith T., Coffey, Robert J., Washington, M. Kay, Goettel, Jeremy A., Lau, Ken S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725941/
https://ncbi.nlm.nih.gov/pubmed/32828819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.08.029
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