Single Cell Transcriptional Analyses Identify Lineage-Specific Epithelial Responses to Inflammation and Metaplastic Development in the Gastric Corpus

BACKGROUND & AIMS: Chronic atrophic gastritis can lead to gastric metaplasia and increase risk of gastric adenocarcinoma. Metaplasia is a precancerous lesion associated with an increased risk for carcinogenesis, but the mechanism(s) by which inflammation induces metaplasia are poorly understood....

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Publicado en:Gastroenterology
Main Authors: Bockerstett, Kevin A., Lewis, Scott A., Noto, Christine N., Ford, Eric L., Saenz, José B., Jackson, Nicholas M., Ahn, Tae-Hyuk, Mills, Jason C., DiPaolo, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725914/
https://ncbi.nlm.nih.gov/pubmed/32835664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.08.027
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