Single-cell transcriptional analyses of spasmolytic polypeptide-expressing metaplasia arising from acute drug injury and chronic inflammation in the stomach

OBJECTIVE: Spasmolytic polypeptide-expressing metaplasia (SPEM) is a regenerative lesion in the gastric mucosa and is a potential precursor to intestinal metaplasia/gastric adenocarcinoma in a chronic inflammatory setting. The goal of these studies was to define the transcriptional changes associate...

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Udgivet i:Gut
Main Authors: Bockerstett, Kevin A, Lewis, Scott A, Wolf, Kyle J, Noto, Christine N, Jackson, Nicholas M, Ford, Eric L, Ahn, Tae-Hyuk, DiPaolo, Richard J
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2020
Fag:
Stomach
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282188/
https://ncbi.nlm.nih.gov/pubmed/31481545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-318930
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