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A Neurotoxic Ménage-à-trois: Glutamate, Calcium, and Zinc in the Excitotoxic Cascade

Fifty years ago, the seminal work by John Olney provided the first evidence of the neurotoxic properties of the excitatory neurotransmitter glutamate. A process hereafter termed excitotoxicity. Since then, glutamate-driven neuronal death has been linked to several acute and chronic neurological cond...

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Udgivet i:Front Mol Neurosci
Main Authors: Granzotto, Alberto, Canzoniero, Lorella M. T., Sensi, Stefano L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725690/
https://ncbi.nlm.nih.gov/pubmed/33324162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2020.600089
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