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Wnt3 distribution in the zebrafish brain is determined by expression, diffusion and multiple molecular interactions

Wnt3 proteins are lipidated and glycosylated signaling molecules that play an important role in zebrafish neural patterning and brain development. However, the transport mechanism of lipid-modified Wnts through the hydrophilic extracellular environment for long-range action remains unresolved. Here...

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Publicado en:eLife
Autores principales: Veerapathiran, Sapthaswaran, Teh, Cathleen, Zhu, Shiwen, Kartigayen, Indira, Korzh, Vladimir, Matsudaira, Paul T, Wohland, Thorsten
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725503/
https://ncbi.nlm.nih.gov/pubmed/33236989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59489
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