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Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host

Metabolism of host-targeted drugs by the microbiome can substantially impact host treatment success. However, since many host-targeted drugs inadvertently hamper microbiome growth, repeated drug administration can lead to microbiome evolutionary adaptation. We tested if evolved bacterial resistance...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Rosener, Brittany, Sayin, Serkan, Oluoch, Peter O, García González, Aurian P, Mori, Hirotada, Walhout, Albertha JM, Mitchell, Amir
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725501/
https://ncbi.nlm.nih.gov/pubmed/33252330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59831
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