AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9

The switch from centrosomal microtubule-organizing centers (MTOCs) to non-centrosomal MTOCs during differentiation is poorly understood. Here, we identify AKAP6 as key component of the nuclear envelope MTOC. In rat cardiomyocytes, AKAP6 anchors centrosomal proteins to the nuclear envelope through it...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Vergarajauregui, Silvia, Becker, Robert, Steffen, Ulrike, Sharkova, Maria, Esser, Tilman, Petzold, Jana, Billing, Florian, Kapiloff, Michael S, Schett, George, Thievessen, Ingo, Engel, Felix B
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725499/
https://ncbi.nlm.nih.gov/pubmed/33295871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61669
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