Late endosomes promote microglia migration via cytosolic translocation of immature protease cathD

Organelle transport requires dynamic cytoskeleton remodeling, but whether cytoskeletal dynamics are, in turn, regulated by organelles remains elusive. Here, we demonstrate that late endosomes, a type of prelysosomal organelles, facilitate actin-cytoskeleton remodeling via cytosolic translocation of...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Liu, Yi-Jun, Zhang, Ting, Cheng, Daxiao, Yang, Junhua, Chen, Sicong, Wang, Xingyue, Li, Xia, Duan, Duo, Lou, Huifang, Zhu, Liya, Luo, Jianhong, Ho, Margaret S., Wang, Xiao-Dong, Duan, Shumin
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725477/
https://ncbi.nlm.nih.gov/pubmed/33298434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba5783
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