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PET imaging and pharmacological therapy targeting carbonic anhydrase-IX high-expressing tumors using US2 platform based on bivalent ureidosulfonamide

Carbonic anhydrase-IX (CA-IX) is attracting much attention as a target molecule for cancer treatment since high expression of CA-IX can lead to a poor prognosis of patients. We previously reported low-molecular-weight (111)In/(90)Y complexes with a bivalent ureidosulfonamide scaffold ([(111)In/(90)Y...

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Udgivet i:PLoS One
Main Authors: Iikuni, Shimpei, Watanabe, Hiroyuki, Shimizu, Yoichi, Nakamoto, Yuji, Ono, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725290/
https://ncbi.nlm.nih.gov/pubmed/33296398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0243327
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