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Increased [(18)F]FMISO accumulation under hypoxia by multidrug-resistant protein 1 inhibitors
BACKGROUND: [(18)F]Fluoromisonidazole ([(18)F]FMISO) is a PET imaging probe widely used for the detection of hypoxia. We previously reported that [(18)F]FMISO is metabolized to the glutathione conjugate of the reduced form in hypoxic cells. In addition, we found that the [(18)F]FMISO uptake level va...
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| Publicat a: | EJNMMI Res |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7835267/ https://ncbi.nlm.nih.gov/pubmed/33492449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-021-00752-3 |
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