The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin

BACKGROUND: The huntingtin-associated protein 40 (HAP40) abundantly interacts with huntingtin (HTT), the protein that is altered in Huntington’s disease (HD). Therefore, we analysed the evolution of HAP40 and its interaction with HTT. RESULTS: We found that in amniotes HAP40 is encoded by a single-e...

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Bibliographic Details
Published in:BMC Evol Biol
Main Authors: Seefelder, Manuel, Alva, Vikram, Huang, Bin, Engler, Tatjana, Baumeister, Wolfgang, Guo, Qiang, Fernández-Busnadiego, Rubén, Lupas, Andrei N., Kochanek, Stefan
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7725122/
https://ncbi.nlm.nih.gov/pubmed/33297953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-020-01705-5
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