An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer

Chondroitin sulfate (CS) is the placental receptor for the VAR2CSA malaria protein, expressed at the surface of infected erythrocytes during Plasmodium falciparum infection. Infected cells adhere to syncytiotrophoblasts or get trapped within the intervillous space by binding to a determinant in a 4-...

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Detalhes bibliográficos
Publicado no:Glycobiology
Principais autores: Toledo, Alejandro Gómez, Pihl, Jessica, Spliid, Charlotte B, Persson, Andrea, Nilsson, Jonas, Pereira, Marina Ayres, Gustavsson, Tobias, Choudhary, Swati, Zarni Oo, Htoo, Black, Peter C, Daugaard, Mads, Esko, Jeffrey D, Larson, Göran, Salanti, Ali, Clausen, Thomas Mandel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Glycan Recognition
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724742/
https://ncbi.nlm.nih.gov/pubmed/32337544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwaa039
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