Oncofetal Chondroitin Sulfate Glycosaminoglycans are Key Players in Integrin Signaling and Tumor Cell Motility

Many tumors express proteoglycans modified with oncofetal chondroitin sulfate glycosaminoglycan chains (ofCS), which are normally restricted to the placenta. However, the role of ofCS in cancer is largely unknown. The function of ofCS in cancer was analyzed using the recombinant ofCS-binding VAR2CSA...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Clausen, Thomas Mandel, Pereira, Marina Ayres, Al Nakouzi, Nader, Oo, Htoo Zarni, Agerbæk, Mette Ø, Lee, Sherry, Ørum-Madsen, Maj Sofie, Christensen, Anders Riis, El-Naggar, Amal, Grandgenett, Paul M., Grem, Jean L., Hollingsworth, Michael A., Holst, Peter J., Theander, Thor, Sorensen, Poul H., Daugaard, Mads, Salanti, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136311/
https://ncbi.nlm.nih.gov/pubmed/27655130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0103
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