Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity

SARS-CoV-2 infection triggers highly variable host responses and causes varying degrees of illness in humans. We sought to harness the peripheral blood mononuclear cell (PBMC) response over the course of illness to provide insight into COVID-19 physiology. We analyzed PBMCs from subjects with variab...

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Detalhes bibliográficos
Publicado no:bioRxiv
Main Authors: Giroux, Nicholas S., Ding, Shengli, McClain, Micah T., Burke, Thomas W., Petzold, Elizabeth, Chung, Hong A., Palomino, Grecia R., Wang, Ergang, Xi, Rui, Bose, Shree, Rotstein, Tomer, Nicholson, Bradly P., Chen, Tianyi, Henao, Ricardo, Sempowski, Gregory D., Denny, Thomas N., Ko, Emily R., Ginsburg, Geoffrey S., Kraft, Bryan D., Tsalik, Ephraim L., Woods, Christopher W., Shen, Xiling
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724678/
https://ncbi.nlm.nih.gov/pubmed/33300002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.12.04.412155
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