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Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches

In order to elucidate novel aspects of the host response to SARS-CoV-2 we performed RNA sequencing on peripheral blood samples across 77 timepoints from 46 subjects with COVID-19 and compared them to subjects with seasonal coronavirus, influenza, bacterial pneumonia, and healthy controls. Early SARS...

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Pubblicato in:medRxiv
Autori principali: McClain, Micah T., Constantine, Florica J., Henao, Ricardo, Liu, Yiling, Tsalik, Ephraim L., Burke, Thomas W., Steinbrink, Julie M., Petzold, Elizabeth, Nicholson, Bradly P., Rolfe, Robert, Kraft, Bryan D., Kelly, Matthew S., Sempowski, Gregory D., Denny, Thomas N., Ginsburg, Geoffrey S., Woods, Christopher W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7386527/
https://ncbi.nlm.nih.gov/pubmed/32743603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.07.20.20155507
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