Embryonic Stem Cell Differentiation Is Regulated by SET through Interactions with p53 and β-Catenin

The multifunctional histone chaperone, SET, is essential for embryonic development in the mouse. Previously, we identified SET as a factor that is rapidly downregulated during embryonic stem cell (ESC) differentiation, suggesting a possible role in the maintenance of pluripotency. Here, we explore S...

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Udgivet i:Stem Cell Reports
Main Authors: Harikumar, Arigela, Lim, Patrick S.L., Nissim-Rafinia, Malka, Park, Jung Eun, Sze, Siu Kwan, Meshorer, Eran
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724474/
https://ncbi.nlm.nih.gov/pubmed/33296674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.11.004
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