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Direct reprogramming of hepatocytes into insulin-producing cells for anti-diabetic treatment by ultrasound-targeted microbubble destruction enhanced hydrodynamic gene delivery

In animal models, hepatocytes can be reprogrammed into insulin-producing cells (IPCs) for a novel antidiabetic treatment. However, the potential for an immunologic reaction and issues with gene integration of the viral vehicle hamper system efficacy. Here, we adopted an Ultrasound Targeted Microbubb...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Transl Res
Päätekijät: Yang, Xiao-Fei, Wang, Han-Yue, Lu, Wei-Lin, Ma, Wei, Zhang, Hai, Li, Fu-Rong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: e-Century Publishing Corporation 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724341/
https://ncbi.nlm.nih.gov/pubmed/33312366
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