Ultrasound-targeted Microbubble Destruction-mediated Gene Delivery Into Canine Livers

Ultrasound (US) was applied to a targeted canine liver lobe simultaneously with injection of plasmid DNA (pDNA)/microbubble (MB) complexes into a portal vein (PV) segmental branch and occlusion of the inferior vena cava (IVC) to facilitate DNA uptake. By using a 1.1 MHz, 13 mm diameter transducer, a...

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Bibliografiske detaljer
Main Authors:	Noble, Misty L, Kuhr, Christian S, Graves, Scott S, Loeb, Keith R, Sun, Samuel S, Keilman, George W, Morrison, Kyle P, Paun, Marla, Storb, Rainer F, Miao, Carol H
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2013
Fag:	Original Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3776626/ https://ncbi.nlm.nih.gov/pubmed/23732985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.107
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Ultrasound-targeted Microbubble Destruction-mediated Gene Delivery Into Canine Livers

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