WZ4003 sensitizes non-small cell lung cancer cells to gefitinib via inhibition of ARK5 and epithelial-to-mesenchymal transition

Gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, is used as a first-line treatment for advanced non-small cell lung cancer (NSCLC); however, its utility is hampered by the development of chemoresistance. This study aimed to investigate the synergistic role of WZ4003, a novel...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Chen, Jiabin, Zhang, Shufen, Zheng, Xiaoxiao, Mao, Jiayan, Xie, Shangzhi, Chen, Wei, Ran, Xiangui
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724321/
https://ncbi.nlm.nih.gov/pubmed/33312374
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