The effect of Smad2- and Smad3-targeting RNA interference on extracellular matrix synthesis in rat fibroblasts of peritoneal adhesion tissues

Fibroblasts migrating to peritoneum injuries play an important role in the development of postoperative peritoneal adhesions due to the excessive synthesis and deposition of extracellular matrix (ECM). This effect is mainly induced by the transforming growth factor-β (TGF-β). Studies indicate that e...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Zeng, Xuxin, Lu, Bin, Wang, Fang, Mao, Jianwen, Deng, Lulu, Li, Yanping, Hou, Lianbing
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724320/
https://ncbi.nlm.nih.gov/pubmed/33312378
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