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Structure-Function of Neuronal Nicotinic Acetylcholine Receptor Inhibitors Derived From Natural Toxins

Neuronal nicotinic acetylcholine receptors (nAChRs) are prototypical cation-selective, ligand-gated ion channels that mediate fast neurotransmission in the central and peripheral nervous systems. nAChRs are involved in a range of physiological and pathological functions and hence are important thera...

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Pubblicato in:Front Neurosci
Autori principali: Ho, Thao N. T., Abraham, Nikita, Lewis, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723979/
https://ncbi.nlm.nih.gov/pubmed/33324158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.609005
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