MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis

Our previous study demonstrated that the methyl-CpG-binding domain protein 2 (MBD2) mediates vancomycin (VAN)-induced acute kidney injury (AKI). However, the role and regulation of MBD2 in septic AKI are unknown. Herein, MBD2 was induced by lipopolysaccharide (LPS) in Boston University mouse proxima...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Xie, Yuxin, Liu, Bohao, Pan, Jian, Liu, Jiamiao, Li, Xiaozhou, Li, Huiling, Qiu, Shuangfa, Xiang, Xudong, Zheng, Peiling, Chen, Junxiang, Yuan, Yunchang, Dong, Zheng, Zhang, Dongshan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723772/
https://ncbi.nlm.nih.gov/pubmed/33335794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.09.028
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