MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI

Despite DNA methylation occurred in acute kidney injury (AKI), how it influenced progression of AKI remains unclear. Methyl-CpG-binding domain protein 2 (MBD2), a protein readers of methylation, was used to analyze the impact of DNA methylation on vancomycin (VAN)-induced AKI. Here, in cultured huma...

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Vydáno v:Cell Death Dis
Hlavní autoři: Wang, Juan, Li, Huiling, Qiu, Shuangfa, Dong, Zheng, Xiang, Xudong, Zhang, Dongshan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682674/
https://ncbi.nlm.nih.gov/pubmed/29022913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.509
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