Metalloprotease ADAMTS-1 decreases cell migration and invasion modulating the spatiotemporal dynamics of Cdc42 activity

ADAMTSs (A Disintegrin And Metalloproteinase with ThromboSpondin motifs) are secreted proteases dependent on Zn(2+) / Ca(2+), involved in physiological and pathological processes and are part of the extracellular matrix (ECM). Here, we investigated if ADAMTS-1 is required for invasion and migration...

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Bibliografske podrobnosti
izdano v:Cell Signal
Main Authors: de Assis Lima, Maíra, da Silva, Suély Vieira, Serrano-Garrido, Orlando, Hülsemann, Maren, Santos Neres, Luana, Rodríguez-Manzaneque, Juan Carlos, Hodgson, Louis, Freitas, Vanessa M
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7723338/
https://ncbi.nlm.nih.gov/pubmed/33161094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109827
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