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Recombinant rubella vectors elicit SIV Gag-specific T cell responses with cytotoxic potential in rhesus macaques

Live-attenuated rubella vaccine strain RA27/3 has been demonstrated to be safe and immunogenic in millions of children. The vaccine strain was used to insert SIV gag sequences and the resulting rubella vectors were tested in rhesus macaques alone and together with SIV gag DNA in different vaccine pr...

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Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Rosati, Margherita, Alicea, Candido, Kulkarni, Viraj, Virnik, Konstantin, Hockenbury, Max, Sardesai, Niranjan Y., Pavlakis, George N., Valentin, Antonio, Berkower, Ira, Felber, Barbara K.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722989/
https://ncbi.nlm.nih.gov/pubmed/25802183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.02.067
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