Expression of complete SIV p27 Gag and HIV gp120 engineered outer domains targeted by broadly neutralizing antibodies in live rubella vectors

Infection with HIV or SIV often elicits a potent immune response to viral antigens. This includes T cells and antibodies specific for Gag and Env antigens. In contrast, when given as a vaccine, the same antigens have been weak immunogens, unable to elicit antibodies with comparable titer, durability...

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Virnik, Konstantin, Nesti, Edmund, Dail, Cody, Hockenbury, Max, Ni, Yisheng, Felber, Barbara K., Schief, William R., Berkower, Ira
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886187/
https://ncbi.nlm.nih.gov/pubmed/28483193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.04.047
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