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Loss of miR-100 and miR-125b results in cancer stem cell properties through IGF2 upregulation in hepatocellular carcinoma

Stemness factors control microRNA expression in cancer stem cells. Downregulation of miR-100 and miR-125b is associated with tumor progression and prognosis of various cancers. Comparing miRNA profiling of patient-derived tumorsphere (TS) and adherent (2D) hepatocellular carcinoma cells, miR-100 and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Seol, Hyang Sook, Akiyama, Yoshimitsu, Lee, San-Eun, Shimada, Shu, Jang, Se Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722933/
https://ncbi.nlm.nih.gov/pubmed/33293585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77960-9
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