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Androgen receptor signalling impairs docetaxel efficacy in castration-resistant prostate cancer
Androgen receptor (AR) signalling drives neoplastic growth and therapy resistance in prostate cancer. Recent clinical data show that docetaxel combined with androgen deprivation therapy improves outcome in hormone-sensitive disease. We studied whether testosterone and AR signalling interferes with d...
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Foilsithe in: | Br J Cancer |
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Main Authors: | , , , , , , , , , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Nature Publishing Group UK
2020
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7722857/ https://ncbi.nlm.nih.gov/pubmed/32989230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01105-y |
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