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Lack of rewarding effects of a soluble epoxide hydrolase inhibitor TPPU in mice: Comparison with morphine

AIM: Although opioids have been used as treatment of neuropathic pain, opioids have abuse potential in humans. Since soluble epoxide hydrolase (sEH) in the metabolism of polyunsaturated fatty acids plays a key role in the pain, sEH inhibitors would be promising new therapeutic drugs for neuropathic...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacol Rep
Main Authors: Wan, Xiayun, Fujita, Yuko, Chang, Lijia, Wei, Yan, Ma, Li, Wuyun, Gerile, Pu, Yaoyu, Hammock, Bruce D., Hashimoto, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722641/
https://ncbi.nlm.nih.gov/pubmed/32896112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/npr2.12136
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