Perioperative Dexmedetomidine attenuates brain ischemia reperfusion injury possibly via up-regulation of astrocyte Connexin 43

BACKGROUND: Astrocyte Connexin 43 (Cx43) is essential for the trophic and protective support of neurons during brain ischemia reperfusion (I/R) injury. It is believed that dexmedetomidine participates in Cx43-mediated effects. However, its mechanisms remained unclear. This study aims to address the...

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Détails bibliographiques
Publié dans:BMC Anesthesiol
Auteurs principaux: Zheng, Xiaoyang, Cai, Xiaoying, Ye, Fang, Li, Ying, Wang, Qin, Zuo, Zhiyi, Huang, Wenqi, Wang, Zhongxing
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722427/
https://ncbi.nlm.nih.gov/pubmed/33287729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12871-020-01211-7
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