Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing

BACKGROUND: The presence of nuclear mitochondrial DNA (numtDNA) has been reported within several nuclear genomes. Next to mitochondrial protein-coding genes, numtDNA sequences also encode for mitochondrial tRNA genes. However, the biological roles of numtDNA remain elusive. RESULTS: Employing in sil...

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Publicado en:Genome Biol
Autores principales: Hoser, Simon M., Hoffmann, Anne, Meindl, Andreas, Gamper, Maximilian, Fallmann, Jörg, Bernhart, Stephan H., Müller, Lisa, Ploner, Melanie, Misslinger, Matthias, Kremser, Leopold, Lindner, Herbert, Geley, Stephan, Schaal, Heiner, Stadler, Peter F., Huettenhofer, Alexander
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722341/
https://ncbi.nlm.nih.gov/pubmed/33292386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02199-6
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