Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing

BACKGROUND: The presence of nuclear mitochondrial DNA (numtDNA) has been reported within several nuclear genomes. Next to mitochondrial protein-coding genes, numtDNA sequences also encode for mitochondrial tRNA genes. However, the biological roles of numtDNA remain elusive. RESULTS: Employing in sil...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Hoser, Simon M., Hoffmann, Anne, Meindl, Andreas, Gamper, Maximilian, Fallmann, Jörg, Bernhart, Stephan H., Müller, Lisa, Ploner, Melanie, Misslinger, Matthias, Kremser, Leopold, Lindner, Herbert, Geley, Stephan, Schaal, Heiner, Stadler, Peter F., Huettenhofer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722341/
https://ncbi.nlm.nih.gov/pubmed/33292386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02199-6
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