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A transgene targeted to the zebrafish nkx2.4b locus drives specific GFP expression and disrupts thyroid development
BACKGROUND: With the goal of labeling and manipulating the zebrafish hypothalamus, we sought to target a gfp transgene to the expression domains of nkx2.4b, a gene expressed during hypothalamic and thyroid development. We combined TALENs mediated mutagenesis with a targeting construct to enable inse...
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| Udgivet i: | Dev Dyn |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7722092/ https://ncbi.nlm.nih.gov/pubmed/32644242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.224 |
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