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Metabolism and pharmacokinetics of a novel polyphenol fatty acid ester phloridzin docosahexaenoate in Balb/c female mice

Flavonoids are known to undergo phase II metabolism and produce metabolites with similar or stronger biological effects compared to the parent flavonoids. However, the limited cellular uptake and bioavailability restrict their clinical use. We synthesized phloridzin docosahexaenoate (PZ-DHA), a nove...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Fernando, Wasundara, Goralski, Kerry B., Hoskin, David W., Rupasinghe, H. P. Vasantha
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721897/
https://ncbi.nlm.nih.gov/pubmed/33288802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78369-0
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