Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected

In Alzheimer’s disease (AD), tau phosphorylation in the brain and its subsequent release into cerebrospinal fluid (CSF) and blood is a dynamic process that changes during disease evolution. The main aim of our study was to characterize the pattern of changes in phosphorylated tau (p‐tau) in the prec...

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Publicado no:EMBO Mol Med
Main Authors: Suárez‐Calvet, Marc, Karikari, Thomas K, Ashton, Nicholas J, Lantero Rodríguez, Juan, Milà‐Alomà, Marta, Gispert, Juan Domingo, Salvadó, Gemma, Minguillon, Carolina, Fauria, Karine, Shekari, Mahnaz, Grau‐Rivera, Oriol, Arenaza‐Urquijo, Eider M, Sala‐Vila, Aleix, Sánchez‐Benavides, Gonzalo, González‐de‐Echávarri, José Maria, Kollmorgen, Gwendlyn, Stoops, Erik, Vanmechelen, Eugeen, Zetterberg, Henrik, Blennow, Kaj, Molinuevo, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7721364/
https://ncbi.nlm.nih.gov/pubmed/33169916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012921
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