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Microarray analysis identifies defects in regenerative and immune response pathways in COPD airway basal cells

BACKGROUND: Airway basal cells are specialised stem cells and regenerate airway epithelium. Airway basal cells isolated from patients with COPD regenerate airway epithelium with an abnormal phenotype. We performed gene expression analysis to gain insights into the defective regenerative programme in...

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Detalhes bibliográficos
Publicado no:ERJ Open Res
Main Authors: Pineau, Fanny, Shumyatsky, Gabriella, Owuor, Nicole, Nalamala, Nisha, Kotnala, Sudhir, Bolla, Sudhir, Marchetti, Nathaniel, Kelsen, Steven, Criner, Gerard J., Sajjan, Uma S.
Formato: Artigo
Idioma:Inglês
Publicado em: European Respiratory Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720690/
https://ncbi.nlm.nih.gov/pubmed/33313308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00656-2020
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