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Re-engineering Natural Products to Engage New Biological Targets

Natural products have a long history in drug discovery, with their inherent biological activity often tailored by medicinal chemists to arrive at the final drug product. This process is illustrated by numerous examples, including the conversion of epothilone to ixabepilone, erythromycin to azithromy...

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Publicat a:Nat Prod Rep
Autors principals: Motika, Stephen E., Hergenrother, Paul J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720426/
https://ncbi.nlm.nih.gov/pubmed/33034322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0np00059k
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