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Re-engineering Natural Products to Engage New Biological Targets

Natural products have a long history in drug discovery, with their inherent biological activity often tailored by medicinal chemists to arrive at the final drug product. This process is illustrated by numerous examples, including the conversion of epothilone to ixabepilone, erythromycin to azithromy...

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Detalhes bibliográficos
Publicado no:Nat Prod Rep
Main Authors: Motika, Stephen E., Hergenrother, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720426/
https://ncbi.nlm.nih.gov/pubmed/33034322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0np00059k
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