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Overlapping-sample Mendelian randomisation with multiple exposures: a Bayesian approach

BACKGROUND: Mendelian randomization (MR) has been widely applied to causal inference in medical research. It uses genetic variants as instrumental variables (IVs) to investigate putative causal relationship between an exposure and an outcome. Traditional MR methods have mainly focussed on a two-samp...

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Detalles Bibliográficos
Publicado en:BMC Med Res Methodol
Main Authors: Zou, Linyi, Guo, Hui, Berzuini, Carlo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720408/
https://ncbi.nlm.nih.gov/pubmed/33287714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01170-0
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