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Overlapping-sample Mendelian randomisation with multiple exposures: a Bayesian approach

BACKGROUND: Mendelian randomization (MR) has been widely applied to causal inference in medical research. It uses genetic variants as instrumental variables (IVs) to investigate putative causal relationship between an exposure and an outcome. Traditional MR methods have mainly focussed on a two-samp...

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Bibliografiske detaljer
Udgivet i:BMC Med Res Methodol
Main Authors: Zou, Linyi, Guo, Hui, Berzuini, Carlo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720408/
https://ncbi.nlm.nih.gov/pubmed/33287714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01170-0
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