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Acute Alcohol Intoxication Impairs Sonic Hedgehog-Gli1 Signaling and Activation of Primitive Hematopoietic Precursor Cells in the Early Stage of Host Response to Bacteremia
BACKGROUND: Activation of hematopoietic stem cells [HSCs, lineage(lin)(−)stem cell growth factor receptor (c-kit)(+)stem cell antigen-1(Sca-1)(+), or LKS cells in mice] is critical for initiating the granulopoietic response. This study determined the effect of alcohol exposure on sonic hedgehog (SHH...
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| Udgivet i: | Alcohol Clin Exp Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720280/ https://ncbi.nlm.nih.gov/pubmed/32772391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14429 |
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