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A microbial metabolite synergizes with endogenous serotonin to trigger C. elegans reproductive behavior
Natural products are a major source of small-molecule therapeutics, including those that target the nervous system. We have used a simple serotonin-dependent behavior of the roundworm Caenorhabditis elegans, egg laying, to perform a behavior-based screen for natural products that affect serotonin si...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7720207/ https://ncbi.nlm.nih.gov/pubmed/33199611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017918117 |
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