Lack of adipocyte purinergic P2Y(6) receptor greatly improves whole body glucose homeostasis

Uridine diphosphate (UDP)-activated purinergic receptor P2Y(6) (P2Y(6)R) plays a crucial role in controlling energy balance through central mechanisms. However, P2Y(6)R’s roles in peripheral tissues regulating energy and glucose homeostasis remain unexplored. Here, we report the surprising finding t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Jain, Shanu, Pydi, Sai P., Toti, Kiran S., Robaye, Bernard, Idzko, Marco, Gavrilova, Oksana, Wess, Jürgen, Jacobson, Kenneth A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2020
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720204/
https://ncbi.nlm.nih.gov/pubmed/33199639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006578117
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