Lack of adipocyte purinergic P2Y(6) receptor greatly improves whole body glucose homeostasis

Uridine diphosphate (UDP)-activated purinergic receptor P2Y(6) (P2Y(6)R) plays a crucial role in controlling energy balance through central mechanisms. However, P2Y(6)R’s roles in peripheral tissues regulating energy and glucose homeostasis remain unexplored. Here, we report the surprising finding t...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Jain, Shanu, Pydi, Sai P., Toti, Kiran S., Robaye, Bernard, Idzko, Marco, Gavrilova, Oksana, Wess, Jürgen, Jacobson, Kenneth A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720204/
https://ncbi.nlm.nih.gov/pubmed/33199639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006578117
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