Replisome bypass of a protein-based R-loop block by Pif1

Efficient and faithful replication of the genome is essential to maintain genome stability. Replication is carried out by a multiprotein complex called the replisome, which encounters numerous obstacles to its progression. Failure to bypass these obstacles results in genome instability and may facil...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Schauer, Grant D., Spenkelink, Lisanne M., Lewis, Jacob S., Yurieva, Olga, Mueller, Stefan H., van Oijen, Antoine M., O’Donnell, Michael E.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7720201/
https://ncbi.nlm.nih.gov/pubmed/33199603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020189117
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